This is a great interview with Kevin Smith the writer and director well known for Clerks and recently the horror film, Red State. His advice is for people who are just starting out about to write their first script and/or finance their first movie, however I think his advice also applies to any independent creative venture. At the beginning of he starts slow but as he gets rolling his advice becomes more potent.
It is necessary to have a reasonable amount of unreasonability to even become a filmmaker.
I known that I certainly faced many doubts about walking the path of the filmmaker. To some extent it is an unreasonable profession, as least that is what you will be told by someone close to you sooner or later. To be in this business you have to be strong about what you want to say and the path that you have choosen to do it.